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2 A3|2 19.1 cM Start 26,913,381 End 26,916,530 pattern Molecular function • • Cellular component • • • • • Biological process • • • • • • • • Sources: / Species Human Mouse RefSeq (mRNA) RefSeq (protein) Location (UCSC) search Surfeit locus protein 1 is a that in humans is encoded by the SURF1. Function [ ] This gene encodes a protein localized to the and thought to be involved in the biogenesis of the complex. The protein is a member of the SURF1 family, which includes the related yeast protein SHY1 and protein RP733. The gene is located in the gene cluster, a group of very tightly linked genes that do not share sequence similarity, where it shares a bidirectional promoter with on the opposite strand. Defects in this gene are a cause of, a severe neurological disorder that is commonly associated with systemic cytochrome c oxidase deficiency. References [ ].
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• ^ -, May 2017 • ^ -, May 2017 •. • Yon J, Jones T, Garson K, Sheer D, Fried M (March 1993). 'The organization and conservation of the human Surfeit gene cluster and its localization telomeric to the c-abl and can proto-oncogenes at chromosome band 9q34.1'. Human Molecular Genetics. 2 (3): 237–40... • Zhu Z, Yao J, Johns T, Fu K, De Bie I, Macmillan C, Cuthbert AP, Newbold RF, Wang J, Chevrette M, Brown GK, Brown RM, Shoubridge EA (December 1998).
'SURF1, encoding a factor involved in the biogenesis of cytochrome c oxidase, is mutated in Leigh syndrome'. Nature Genetics. 20 (4): 337–43... Further reading [ ].
2 A3|2 19.1 cM Start 26,913,381 End 26,916,530 pattern Molecular function • • Cellular component • • • • • Biological process • • • • • • • • Sources: / Species Human Mouse RefSeq (mRNA) RefSeq (protein) Location (UCSC) search Surfeit locus protein 1 is a that in humans is encoded by the SURF1. Function [ ] This gene encodes a protein localized to the and thought to be involved in the biogenesis of the complex.
The protein is a member of the SURF1 family, which includes the related yeast protein SHY1 and protein RP733. The gene is located in the gene cluster, a group of very tightly linked genes that do not share sequence similarity, where it shares a bidirectional promoter with on the opposite strand. Defects in this gene are a cause of, a severe neurological disorder that is commonly associated with systemic cytochrome c oxidase deficiency. References [ ]. • ^ -, May 2017 • ^ -, May 2017 •. • Yon J, Jones T, Garson K, Sheer D, Fried M (March 1993).
'The organization and conservation of the human Surfeit gene cluster and its localization telomeric to the c-abl and can proto-oncogenes at chromosome band 9q34.1'. Human Molecular Genetics. 2 (3): 237–40... • Zhu Z, Yao J, Johns T, Fu K, De Bie I, Macmillan C, Cuthbert AP, Newbold RF, Wang J, Chevrette M, Brown GK, Brown RM, Shoubridge EA (December 1998). 'SURF1, encoding a factor involved in the biogenesis of cytochrome c oxidase, is mutated in Leigh syndrome'. Nature Genetics.